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23.07.2010

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    Which of these are threadlike structures where genes can be found?What are threads of chromosomes called?Are threadlike strands of DNA molecules that carry genetic information?Are threadlike structures made up of DNA that come in 23 pairs with one thành viên of each pair coming from each parent?

2.2 Every cell in the human body toàn thân contains a nucleus, with the exception of red blood cells, which lose this structure as they mature. Within the nucleus are tightly coiled threadlike structures known as chromosomes (see Figure 1). Every chromosome has a long arm and a short arm, with a pinch point known as a ‘centromere’. Humans normally have 23 pairs of chromosomes, one thành viên of each pair derived from the mother and one from the father (see Figure 2). One those pairs consists of the sex chromosomes—with two X chromosomes determining femaleness, and one X and one Y determining maleness. The other 22 chromosomes are known as ‘autosomes’.

2.3 Each chromosome has within it, arranged end-to-end, hundreds or thousands of genes (see Figure 3),[3] each with a specific location, consisting of the inherited genetic material known as DNA. Some chromosomes are significantly larger than others, and some are more densely packed with genes. Under the standard system of identification, scientists have numbered these autosomes from 1–22 in size order (that is, the number of base pairs),[4] with chromosome 1 being the largest (279 million base pairs, and an estimated 2968 genes).[5] Of the sex chromosomes, the X (163 million base pairs and an estimated 1184 genes) is similar in size to chromosome 7, while the Y is the smallest chromosome (51 million base pairs and an estimated 231 genes).[6]

2.4 DNA (deoxy-ribo-nucleic acid) is so called because it consists of a large acid molecule mainly found in the nucleus (nucleic) to which many sugar groups (ribo) that are missing an oxygen molecule (deoxy) are attached. DNA contains a code that directs the ‘expression’ or production of proteins, which form much of the structure of the cell and control the chemical reactions within them. The DNA of each gene is characterised by a unique sequence of bases which, when arranged in triplets (codons) in various orders, represent the ‘genetic code’.[7]

2.5 There are many different definitions for a ‘gene’, but one of the most commonly accepted is that a gene contains all of the information required to determine the expression of a specific protein or a chain of amino acids (a ‘polypeptide’). Sometimes a polypeptide can form a complete protein on its own (as in the case of insulin), but in most cases a number of polypeptides combine to create a single functional protein (as in the case of collagen and globin).

2.6 There are four basic building blocks (nucleotides) for DNA: Adenine (A) and Guanine (G), which are known as ‘purines’; and Thymine (T) and Cytosine (C), which are known as ‘pyrimidines’. These nucleotides link together to form long polynucleotide chains (see Figure 4). A DNA molecule consists of two of these chains, linked together by hydrogen bonds, running in opposite directions. Linkage of the chains follows a strict rule, known as ‘complementary base pairing’:

    the base A can only pair with the base T, and vice versa; and

    the base G can only pair with the base C, and vice versa.

2.7 There are over three billion of these base pairs of DNA making up the human genome. The two chains link together in a ladder-like shape, twisted into the now famous ‘double helix’ shape first described by Watson and Crick in 1953,[8] with sugars and phosphates forming the sides or backbone of the ladder and the base pairs forming the rungs (see Figure 5).

2.8 In humans, genes comprise only a small proportion of the DNA in a cell. Up to 98% of DNA consists of ‘non-coding’ regions—popularly, but incorrectly, referred to as ‘junk DNA’—which are full of repeat sequences, pseudogenes and retroviruses. There are no non-coding portions of DNA in bacteria—there are only genes, each one expressing a specific protein. In recent years, genetic scientists have increasingly come to believe that it is non-coding DNA that may be the basis for the complexity and sophistication of the human genome, which permits only 30,000 genes to produce about 200,000 proteins. A leader in this field, Professor John Mattick AO, Director of the Institute for Molecular Biology the University of Queensland (and a Member of the Australian Health Ethics Committee), has surmised that non-coding DNA forms:

a massive parallel processing system producing secondary signals that integrate and regulate the activity of genes and proteins. In effect, they co-ordinate complex programs involved in the development of complex organisms.[9]

2.9 Proteins are critical components of all cells, determining colour, shape and function. Proteins can have a structural role (such as keratin, from which hair is made), or a functional role in regulating the chemical reactions that occur within each cell (such as the enzymes involved in producing energy for the cell). Proteins are themselves made up of a chain of amino acids. Within the DNA there is a code that determines which amino acids will come together to form that particular protein. The genetic code for each amino acid, consisting of three base sequences, is virtually identical across all living organisms.[10]

2.10 Different genes are switched on and off in different cells, leading to different proteins being made or expressed with different structures, appearances and functions—leading to the production of brain cells, nerve cells, blood cells, and so on. Contemporary stem cell research is based around the idea that it should be possible to learn how to use gene switches to coax stem cells into developing into the specialised cell or tissue needed for therapeutic purposes. Research recent has also begun to focus on ‘epigenetic’ changes to the human genome—subtle modifications to the genome that do not alter the DNA sequence, but may play a role in modulating gene expression. This may explain, for example, why many diseases appear only later in life, and why one twin may develop a genetic-linked disease while the other does not.[11]

2.11 When the instructions in a gene are to be read, the DNA comprising that gene unwinds and the two strands separate. An enzyme called RNA polymerase allows a complementary copy of one strand of the DNA to be made. This copy is made from RNA nucleotides, and is called ‘messenger RNA’ (or mRNA) because it serves to carry the coded genetic information to the protein-producing units in the cell, called ribosomes.[12] This process of reading the message in the DNA is called ‘transcription’. On the ribosomes, the amino acids are assembled in the precise order coded for in the mRNA.[13] The process of converting the message encoded in the RNA (mRNA) to protein using the ribosome is called ‘translation’. When the whole message has been translated, the long chain of amino acids folds itself up into a distinctive shape that depends upon its sequence, and is now known as a ‘protein’ (see Figure 6).[14]

Which of these are threadlike structures where genes can be found?

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA).

What are threads of chromosomes called?

​Chromatid The two “sister” chromatids are joined a constricted region of the chromosome called the centromere. During cell division, spindle fibers attach to the centromere and pull each of the sister chromatids to opposite sides of the cell.

Are threadlike strands of DNA molecules that carry genetic information?

Answer and Explanation: Chromosomes are threadlike strands of DNA molecules that carry genetic information.

Are threadlike structures made up of DNA that come in 23 pairs with one thành viên of each pair coming from each parent?

Among the many things parents hand down to their children are 23 pairs of chromosomes – those thread-like structures in the nucleus of every cell containing the genetic instructions for every person. We inherit a set of 23 chromosomes from our mothers and another set of 23 from our fathers. Tải thêm tài liệu liên quan đến nội dung bài viết Are threadlike tissues that carries the genes and are usually found in pairs?

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